阿荣（Atiwat Lamgul 饰）和小董（Kapon Tongplub 饰）是医学院的学生，某日，两人偷偷潜入停尸房，想要取得尸油和夭折的胎儿。在传说中，死去的胎儿能够实现主人的愿望，而尸油则拥有操纵他人感情的神奇功效。 两人的秘密行动被在医院值班的护工小国发现了，虽然经历了一些波折，阿荣和小董的计划还是成功了，两人实现了愿望，亦得到了他们一直想要得到的东西。然而，之后，两人的身边开始发生一些科学无法解释的诡异事件，没过多久，他们双双命丧黄泉，其状可怖，而看似无辜的小国亦被牵连遭遇了和两人相似的事件，阿荣留下的视频揭露了小国的秘密，原来他亦深陷罪恶的泥潭之中。
警察兼律师Ned Ravine（阿曼德·阿山特 Armand Assante 饰）自以为很了解女人，最近却被一个萍水相逢的女人Lola Cain（肖恩·杨 Sean Young 饰）缠上了，而他的女秘书Laura（雪琳·芬 Sherilyn Fenn 饰）则因为丈夫的变态而神经兮兮。Ned深爱着他的妻子Lana，而Lana却背着他和修车工Frankie偷情，两人为了赢取Ned的巨额保险金，决定铤而走险，将Ned骗上火车将其杀死。同时，Ned的大仇人Max Shady也因为刑满出狱，准备找他报仇。Lana的计划进行得十分顺利，Max也计划在火车上向Ned报仇。然而在火车上，Lana却把枪瞄准了穿着和Ned一样西装的Max......本片恶搞了《双重赔偿》和《本能》等多部影片，笑料百出。
California gold rush, late 1800's: A gun slinging bounty hunter (Mortimer) travels deep into the mountains to find a deadly Apache warrior (Brother Wolf) who is wanted by the law. Along the way he passes through a gold mining Town. The miners help direct Mortimer to the Apache and send him on his way. Mortimer enters the forest and begins to track the Apache. Back in town, the miners un-earth an ancient meteor. They use their pick axes to crack it open. A section of the meteor splits apart and spores explode out of it. The spore surround and infect the entire population of the mining camp. They are transformed into ravenous mutants. After a vicious battle against the Apache warrior, Mortimer exits the forest with his prisoner in shackles. They hike back to the mining town to find them selves surrounded by a horde of blood thirsty mutants. Now Mortimer the gun slinger and Brother Wolf the Warrior must join together to survive the mutant hordes. What ensues is a bloodbath of horror for the Dead and the Damned.
